Evaluation of APR1 Gene Expression in Candida albicans Strains Isolated From Patients With Multiple Sclerosis

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Evaluation of APR1 Gene Expression in Candida albicans Strains Isolated From Patients With Multiple Sclerosis

BACKGROUND Intracellular aspartic proteinase A enzyme is expressed by the APR1 gene and is one of the important factors in the development of systemic candidiasis caused by Candida albicans. OBJECTIVES The aim of this study was to evaluate the expression of the APR1 gene in C. albicans isolates obtained from patients with multiple sclerosis (MS) and from controls. PATIENTS AND METHODS The s...

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evaluation of apr1 gene expression in candida albicans strains isolated from patients with multiple sclerosis

conclusions the results suggested that apr1 gene expression in c. albicans strains isolated from ms patients may be an important factor for invasive c. albicans strains in the progression of ms disease. results there was a statistically significant difference in apr1 gene expression of c. albicans strains between ms patients (mean ± sd: 0.5208 ± 0.11518) and the control group (mean ± sd: 0.7603...

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A Comparative Study on Level of erg11 Gene Expression in Non-albicans Candida Strains Isolated from Patients and Raw Milk

Nowadays, non-albicans Candida are common in human pathogens, and some of these cases were found in milk in the present study. Thanks to its various minerals and vitamins, milk is a good food source for humans and an ideal environment for the growth of microorganisms, including bacteria and fungi. Also, it is an important product in the agricultural sector. Materials and Methods: In the presen...

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Investigation of Mutations of ERG11 Gene in Fluconazole Resistant Strains of Candida Albicans Isolated From Patients With Volvovaginitis in West of Mazandaran

Background and Aims: Candida albicans as an opportunistic fungal pathogen in human is the cause of volvovaginitis candidiasis. Azole resistance is cinsiderable as worldwide problem in treatment of candidiasis. Azole resistance can occur through different mechanisms such as mutation in ERG11 gene. The aim of our study was evaluation of ERG11 gene mutations in fluconazole resistant islotes of C. ...

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ژورنال

عنوان ژورنال: Jundishapur Journal of Microbiology

سال: 2016

ISSN: 2008-3645,2008-4161

DOI: 10.5812/jjm.33292